Cervical Cancer Clinical Trials (as of August 2, 2021)

ENGOT-cx17/GINECO/

Leading group: GINECO

Clinical Trial Study: Anti-PD-L1 Balstilimab vs Investigator Choice Chemotherapy in Patients with Recurrent Cervical Cancer  

Planned number of patients: 495

Participating groups: 

A-AGO,AGO, GEICO, MITO, CEEGOG, SAKK, PGOG, CTI, BGOG, TRSGO, HeCOG

Planned start in 3Q 2021

 

ENGOT-cx16/CEEGOG/CERVANTES

Leading group: CEEGOG

Clinical Trial Study: CERVANTES (CERVical cancer AdjuvaNt Treatment Study)​ - ​An international randomized trial of radical surgery followed by adjuvant  (chemo)radiation versus no further treatment in patients with early-stage, intermediate-risk cervical cancer patients​

Planned number of patients: 514

Participating groups: 

PGOG, BGOG, AGO

Planned start in September 2021

 

ENGOT-cx15/GEICO/102C

Leading group: GEICO

Clinical Trial Study: GOG-3056 EMD Serono 1L Cervical Ph3 chemo/combo  

Planned number of patients: TBA

Participating groups: 

AGO, GINECO, MITO

 

ENGOT-cx13/AGO/FERMATA

Leading group: AGO

Clinical Trial Study: FERMATA Trial: An international randomized double-blind clinical trial of BCD-100 plus platinum-based chemotherapy with and without Bevacizumab versus placebo plus platinum-based chemotherapy with and without Bevacizumab as first-line treatment of subjects with advanced cervical cancer

Planned number of patients: 316

Participating groups: 

A-AGO, BGOG, CEEGOG, NSGO, PGOG

 

ENGOT-cx12/BGOG-cx12

Leading group: BGOG

Clinical Trial Study: Phase 3, randomized controlled trial of Tisotumab Vedotin vs Investigator’s choice chemotherapy in 2nd or 3rd line recurrent cervical cancer

Planned number of patients: 482

Participating groups: 

NSGO, AGO, MITO, GEICO, GINECO, A-AGO, CEEGOG, CTI, NCRI, DGOG, MaNGO, PGOG

US: FPI Feb 2021 , EU: Planned start Q3 2021

 

ENGOT-cx11/MITO/LACC

Leading group: MITO

Clinical Trial Study: A Randomized, Phase 3, Double-Blind Study of Chemoradiotherapy With or Without Pembrolizumab for the Treatment of High-risk, Locally Advanced Cervical Cancer

Planned number of patients: 786

Participating groups: 

MITO, MaNGO, BGOG, Cancer Trial Ireland, GINECO, HeCOG, CEEGOG, GEICO, ISGO, NCRI, G-AGO, NOGGO, NSGO, A-AGO

 

ENGOT-cx10/GEICO/BEATcc

Leading group: GEICO

Clinical Trial Study: A randomized phase III trial of  platinum chemotherapy plus Paclitaxel with Bevacizumab and Atezolizumab versus platinum chemotherapy plus Paclitaxel and Bevacizumab in metastatic (stage IVB), persistent or recurrent carcinoma of the cervix (BEATcc).

Planned number of patients: 404

Participating groups: 

AGO, GINECO, MaNGO, MITO, NSGO,  JGOG, GOG-F

 

ENGOT-cx4/GINECO/SENTICOL

Leading group: GINECO

Clinical Trial Study: International prospective validation trial of sentinel node biopsy in cervical cancer

Planned number of patients: 950

Participating groups: 

AGO, MaNGO, NSGO, DGOG, CEEGOG

 

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Bernstorff Slot
Copenhagen, Denmark

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