Endometrial Cancer Clinical Trials (as of October 2017)

ENGOT-en7/MaNGO/atTEdn

Leading group: MaNGO

Clinical Trial Study: AtTEdn trial: Phase III double-blind randomized placebo controlled trial of Atezolizumab in combination with paclitaxel and carboplatin in women with advanced/recurrent endometrial cancer

Number of patients accrued: 0

Planned number of patients: 496

Participating groups:

TBA

 

 

ENGOT-en6/NSGO/TSR-042

Leading group: NSGO

Clinical Trial Study: A phase III, randomized, open-label study of TSR-042, an Anti-PD-1 monoclonal antibody, versus investigator´s choice chemotherapy in patients with advanced/recurrent endometrial cancer

Number of patients accrued: 0

Planned number of patients: 580

Participating groups:

TBA

 

 

ENGOT-en5/BGOG-en5/SIENDO

Leading group: BGOG

Clinical Trial Study: A randomized phase III trial of maintenance with Selinexor/placebo after combination chemotherapy for patients with advanced or reccurent endometrical cancer

Number of patients accrued: 0

Planned number of patients: 161

Participating groups:

GEICO, NSGO, other groups TBA

 

 

ENGOT-en4/NCRI/STATEC

Leading group: NCRI

Clinical Trial Study:

STATEC: A randomised trial of non-Selective versus selective adjuvant Therapy in high risk Apparent sTage 1 Endometrial Cancer

Number of patients accrued: 6

Planned number of patients: 2000

Participating groups:

DGOG, (ANZGOG)

 

 

ENGOT-en3/NSGO/PALEO

Leading group: NSGO

Clinical Trial Study: A randomized phase II trial of Palbociclib in combination with letrozole versus letrozole for patients with oestrogen receptor positive recurrent endometrial cancer

Number of patients accrued: 4

Planned number of patients: 78

Participating groups:

GEICO, MITO, NOGGO

 

 

ENGOT-en2/NSGO/DGCG

Leading group: NSGO

Clinical Trial Study: Adjuvant chemotherapy in node negative endometrial carcinoma

Number of patients accrued: 181

Planned number of patients: 240

Participating groups:

BGOG, CEEGOG, EORTC, GEICO, ISGO, MaNGO, MITO, NOGGO

 

 

ENGOT-en1/NSGO/FANDANGO

Leading group: NSGO

Clinical Trial Study: A randomized phase II trial of first-line combination chemotherapy with Nintedanib/placebo for patients with advanced or recurrent endometrial cancer

Number of patients accrued: 42

Planned number of patients: 148

Participating groups:

BGOG, GINECO, NOGGO